Runecraft

To start Runecrafting grab Essense' from the General Store or Ironman Store.
Speak to the Mage of Zamorak north of the Well of Goodwill at ::home or at ::shops. Ask him about getting Rune Pouches and he will give you a small pouch.
A message will pop up in-game chat explaining how to acquire the Medium and Large pouches.

Once you have your pouches simply right-click the Mage of Zamorak and teleport to the Abyss and craft the best runes you can.

Check THIS YOUTUBE VIDEO for the fastest XP/hr method in the Abyss.
Use 'X' left-click withdrawal, ESC to close bank, click your pouch, open bank, 'X' left-click withdrawal, click altar.
Using only a large pouch ends up being much easier and the same/ if not more XP/hr than using all pouches together.

Lenegdary Donator Zone has a Nature Altar right next to a bank to speed up training. This altar also provides much much better XP than the Abyss per invy.

Onyx Donator Zone has a Wrath Altar next to a bank. This altar provides a HUGE XP boost per invy too.